MCF Symposium
Our biggest event of the year:
Everything Chromatography & More
Everything Chromatography & More
MCF Invites you to our 44th Annual Symposium!
When: June 10-12, 2025
Where: Heritage Center of Brooklyn Center (formerly Earle Brown), Minneapolis MN
Why: Meet with other separation scientists, attend or give presentations, hear the latest in chromatography research,
meet with vendors, view the latest products, and more!
Where: Heritage Center of Brooklyn Center (formerly Earle Brown), Minneapolis MN
Why: Meet with other separation scientists, attend or give presentations, hear the latest in chromatography research,
meet with vendors, view the latest products, and more!
Important Dates
Abstract Submission Deadline: April 11, 2025
Short Course Registration Deadline: May 31, 2025
Online Registration Deadline: May 31, 2025
*Early bird pricing for Symposium registration is valid until April 30, 2025.
Short Course Registration Deadline: May 31, 2025
Online Registration Deadline: May 31, 2025
*Early bird pricing for Symposium registration is valid until April 30, 2025.
Schedule of Events
Tuesday, June 10
8:30am-4:30pm: Concurrent Short Courses
Wednesday, June 11
8:00am-Noon: Concurrent Short Courses
Noon - 6:00pm: Vendor Exhibits Open
2:30-5:00pm: Vendor Seminars
3:30-6:00pm: Reception in Exhibition Hall
** Registration is NOT required for the Vendor Exhibits and Reception on this day.
Thursday, June 12
7:30am - 5:30 pm: Symposium Breakfast, Keynote, and Technical Program
10:00am - 4:30pm: Vendor Exhibits Open
4:00-4:30pm: Door Prize Drawing & MCF Board Elections
8:30am-4:30pm: Concurrent Short Courses
Wednesday, June 11
8:00am-Noon: Concurrent Short Courses
Noon - 6:00pm: Vendor Exhibits Open
2:30-5:00pm: Vendor Seminars
3:30-6:00pm: Reception in Exhibition Hall
** Registration is NOT required for the Vendor Exhibits and Reception on this day.
Thursday, June 12
7:30am - 5:30 pm: Symposium Breakfast, Keynote, and Technical Program
10:00am - 4:30pm: Vendor Exhibits Open
4:00-4:30pm: Door Prize Drawing & MCF Board Elections
Keynote Presentation:
"Moving Beyond Traditional Chromatography:
Studies of Bio/Chemical and Environmental Interactions
by Affinity-Based Methods"
This year's Keynote Presentation will be given by Dr. David S. Hage from the Department of Chemistry at the University of Nebraska - Lincoln.
Abstract: Chromatography has long been important for the separation and measurement of compounds in complex samples. However, chromatography can also be a powerful means for providing fundamental information on chemical and biochemical interactions. This presentation will illustrate this concept by examining how high-performance affinity chromatography (HPAC) has been used to study binding events in various systems of biomedical or environmental interest. Affinity chromatography represents a diverse set of liquid chromatographic methods that use biologically-related agents as the stationary phase. These binding agents can range from antibodies, proteins, glycoproteins, carbohydrates, and nucleic acids to chiral stationary phases and synthetic analogs or mimics of biological agents. Various strategies will be shown by which HPAC can be used to both study and utilize these materials to determine the binding strengths, reaction rates, and interaction sites for bio/chemical systems. The general principles of these methods will be described, along with recent research that has been conducted in developing new supports, immobilization methods and formats for use in these strategies. Methods based on microscale affinity columns will also be discussed. A wide range of binding strengths and rates can be assessed through these approaches. The emphasis in this presentation will be on applications in which HPAC has been used as a model to investigate drug and solute transport and bioavailability in natural systems. Examples of these applications will include studies of drug and hormone interactions with serum transport agents in the bloodstream and of disease-related changes in these processes. Another set of applications will include studies of binding by human-made microcontaminants, such as antibiotics and other pharmaceuticals, with natural dissolved organic matter and other agents that may be found in water. The advantages and requirements of using HPAC and affinity platforms for these experiments will be examined, as well as the potential extension of these approaches to other applications of interest in biomedical or environmental research.
Biography: David S. Hage is the James Hewett University Professor and a Professor in the Department of Chemistry at the University of Nebraska-Lincoln. His main research interests involve the theory, design and use of new affinity-based separations and methods in high-performance liquid chromatography, capillary electrophoresis, and other systems for the study or analysis of complex samples. Specific interests include chromatographic-based immunoassays; the study of bio/chemical interactions by affinity-based separation methods; the theory and behavior of chiral separations; the production of new supports, such as affinity monoliths, and immobilization schemes for bio-related agents in HPLC; and the creation of miniaturized separation platforms for personalized medicine or environmental studies.
Prof. Hage is the author of over 350 research publications, reviews, and book chapters, including the Handbook of Affinity Chromatography. He is an AAAS Fellow, a member of the National Academy of Clinical Biochemistry, and the Editor-in-Chief for the Journal of Chromatography B. His research in chemical separations and analytical/bioanalytical chemistry has been recognized by his receipt of such honors as the ACS Chromatography Award, the University of Nebraska Outstanding Research and Creative Activity Award, the ISMR/Pierce Award in Affinity Technology, and the EAS Award for Outstanding Achievements in Separation Science.
Prof. Hage is also known for his efforts in education in analytical chemistry and separation science. For instance, he is the lead author of the textbook Analytical Chemistry and Quantitative Analysis, and he is a co-author or contributor to many other texts in analytical chemistry or related fields. His work in education and mentoring has been recognized by the College Distinguished Teaching Award, Excellence in Graduate Education Award, and Lily Sands Legacy Award from the University of Nebraska. In addition, he has received the International Federation of Clinical Chemistry Award for Distinguished Contributions to Education and the American Association for Clinical Chemistry Award for Outstanding Contributions to Education.
Abstract: Chromatography has long been important for the separation and measurement of compounds in complex samples. However, chromatography can also be a powerful means for providing fundamental information on chemical and biochemical interactions. This presentation will illustrate this concept by examining how high-performance affinity chromatography (HPAC) has been used to study binding events in various systems of biomedical or environmental interest. Affinity chromatography represents a diverse set of liquid chromatographic methods that use biologically-related agents as the stationary phase. These binding agents can range from antibodies, proteins, glycoproteins, carbohydrates, and nucleic acids to chiral stationary phases and synthetic analogs or mimics of biological agents. Various strategies will be shown by which HPAC can be used to both study and utilize these materials to determine the binding strengths, reaction rates, and interaction sites for bio/chemical systems. The general principles of these methods will be described, along with recent research that has been conducted in developing new supports, immobilization methods and formats for use in these strategies. Methods based on microscale affinity columns will also be discussed. A wide range of binding strengths and rates can be assessed through these approaches. The emphasis in this presentation will be on applications in which HPAC has been used as a model to investigate drug and solute transport and bioavailability in natural systems. Examples of these applications will include studies of drug and hormone interactions with serum transport agents in the bloodstream and of disease-related changes in these processes. Another set of applications will include studies of binding by human-made microcontaminants, such as antibiotics and other pharmaceuticals, with natural dissolved organic matter and other agents that may be found in water. The advantages and requirements of using HPAC and affinity platforms for these experiments will be examined, as well as the potential extension of these approaches to other applications of interest in biomedical or environmental research.
Biography: David S. Hage is the James Hewett University Professor and a Professor in the Department of Chemistry at the University of Nebraska-Lincoln. His main research interests involve the theory, design and use of new affinity-based separations and methods in high-performance liquid chromatography, capillary electrophoresis, and other systems for the study or analysis of complex samples. Specific interests include chromatographic-based immunoassays; the study of bio/chemical interactions by affinity-based separation methods; the theory and behavior of chiral separations; the production of new supports, such as affinity monoliths, and immobilization schemes for bio-related agents in HPLC; and the creation of miniaturized separation platforms for personalized medicine or environmental studies.
Prof. Hage is the author of over 350 research publications, reviews, and book chapters, including the Handbook of Affinity Chromatography. He is an AAAS Fellow, a member of the National Academy of Clinical Biochemistry, and the Editor-in-Chief for the Journal of Chromatography B. His research in chemical separations and analytical/bioanalytical chemistry has been recognized by his receipt of such honors as the ACS Chromatography Award, the University of Nebraska Outstanding Research and Creative Activity Award, the ISMR/Pierce Award in Affinity Technology, and the EAS Award for Outstanding Achievements in Separation Science.
Prof. Hage is also known for his efforts in education in analytical chemistry and separation science. For instance, he is the lead author of the textbook Analytical Chemistry and Quantitative Analysis, and he is a co-author or contributor to many other texts in analytical chemistry or related fields. His work in education and mentoring has been recognized by the College Distinguished Teaching Award, Excellence in Graduate Education Award, and Lily Sands Legacy Award from the University of Nebraska. In addition, he has received the International Federation of Clinical Chemistry Award for Distinguished Contributions to Education and the American Association for Clinical Chemistry Award for Outstanding Contributions to Education.